The 14 chapters contained in the Chemical Society Reviews of May 2013 devoted to Carbohydrate Chemistry provide a broad survey of recent advances in glycochemisty and chemical glycobiology. The chemical and analytical tools that have been generated for functional studies of glycan are providing great opportunities to make progress in deciphering the biological roles of these complex molecules and developing novel therapeutic agents.
- Carbohydrate Chemistry
- Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics
- Chemical probing of glycans in cells and organisms
- Design of chemical glycosyl donors : does changing ring conformation influence selectivity/reactivity ?
- Carbohydrate microarrays
- Designing a new antifungal glycoconjugate vaccine
- Chemical approaches to study O-GlcNAcylation
- The biosynthesis of nitrogen-, sulfur-, and high-carbon chain-containing sugars
- Chemical assembly of N-glycoproteins : a refined toolbox to address a ubiquitous posttranslational modification
- The development of synthetic antitumour vaccines from mucin glycopeptide antigens
- Lectin microarrays : concept, principle and applications
- Development of fucosyltransferase and fucosidase inhibitors
- Glycopolymer probes of signal transduction
- Bridging lectin binding sites by multivalent carbohydrates