Carbohydrate Chemistry : State of the Art and Challenges for Drug Development An Overview on Structure, Biological Roles, Synthetic Methods and Application as Therapeutics
The book is intended to give a clear and concise review on carbohydrate chemistry and biology, evidencing the biological role, analytical techniques and limitations due to complexity, and their application in medicinal chemistry
[http://www.worldscientific.com/worldscibooks/10.1142/p1013#t=toc]

Structure and Biological Function of Glycoconjugates :
- Glycoproteins : Chemical Features and Biological Roles (Yanhong Li, Xixuan Li and Xi Chen)
- Gangliosphingolipids : Structure and Biological Roles (Sophie Groux-Degroote, Yann Guéardel and Philippe Delannoy)
- Bacterial Lipopolysaccharides : An Overview of Their Structure, Biosynthesis and Immunological Activity (Flaviana Di Lorenzo, Alba Silipo, Rosa Lanzetta, Michelangelo Parrilli and Antonio Molinaro)
Towards Glycomics : Methodologies and Techniques for the Determination of Structure and Activity Relationship :
- Mass Spectrometry : Updates in the Elucidation of Structure of Oligosaccharides (Maria Michela Corsaro)
- Advanced NMR Techniques : Defining Carbohydrate Structures and Ligand-Receptor Interactions (M Álvaro Berbís, Ángeles Canales, Javier Sastre-Martinez, Luca Unione, M C Fernández-Alonso, Pilar Blasco, F Javier Cañada and Jesús Jiménez-Barbero)
- Glycoarrays : An Invaluable Tool for Glycomics (Niels-Christian Reichardt, Sonia Serna and Juan Echevarria)
- Informatics and Analytical Tools for Glycan Analysis and the Development of Biotherapeutics (Catherine A Hayes, Giorgio Carta, Niclas G Karlsson Fergal Duffy and Pauline M Rudd)
Synthetic Challenges : Towards Drug Development :
- Classical Tools for Oligosaccharide Synthesis (Daniel B Werz)
- When Enzymes Do It Better : Enzymatic Glycosylation Methods (Antoni Planas, Magda Faijes and Victoria Codera)
- Automated Chemical Synthesis of Oligosaccharides and Glycoconjugates (Salvatore G Pistorio, Keith J Stine and Alexei V Demchenko)
Carbohydrate-Based Compounds For Medicinal Chemistry Applications :
- Iminosugars : The Potential of Carbohydrate Analogs (Naoki Asano)
- Vaccines against Bacterial Pathogens : A General Overview (Darielys Santana Medero, Dagmar Garcia Rivera, Yury Valdes Balbin and Vicente Verez Bencomo)
- Carbohyd rate-Based Antibacte Current Progress and Future Outlook (Sachin S Shivatare and Chung-Yi Wu)
- Synthetic Vaccines Against Cancers (Michele Fiore, Baptiste Thomas, Gour Chand Daskhan and Olivier Renaudet)
- DC-SIGN as a Target for Drug Development Based on Carbohydrates (Sara Sattin, Franck Fieschi and Anna Bernardi)
- Carbohydrates, Biomaterials, and Tissue Engineering Applications (Laura Russo, Antonella Sgambato, Davide Bini, Ilaria Calloni, Davide Origgi, Fatma Cetin Telli and Laura Cipolla)
- Carbohydrate Multivalent Systems : Synthesis and Therapeutic Opportunities (Jose J Reina and Javier Rojo)
- Antitubercular Drugs Based on Carbohydrate Derivatives (Vishwanath Gaitonde and Steven J Sucheck)
Conclusion :
- Carbohydrate-Based Drugs on the Market : Overview and Future Directions (Matteo Gentili and Oscar Francesconi)