Glycoblocks : A Schematic 3D Representation for Glycans and their Interactions

With structural glycoscience gaining popularity and steadily increasing the deposition rate of three-dimensional structures of glycoproteins, the need for a clear way of depicting these interactions is more pressing than ever.

Finding an unobscured molecular view of these multipartite interactions occurring between the glycan and the proteins is usually far from trivial. As an answer to such an issue, a new representation has been developed under the name of Glycoblocks. Glycoblocks, combines a simplified bonding-network depiction (covering hydrogen bonds and stacking interactions) with the familiar two-dimensional glycan notation used by the glycobiology community.